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550 microorganisms
120 index bacteria
23 resistance genes
PadoBiom® analyzes and evaluates the periodontal microbiome using a patented method based on next-generation sequencing. It tests over 7,000 taxa—including bacteria, fungi, viruses, and parasites—and over 550 oral microorganisms to calculate a dysbiosis index based on more than 120 disease- and health-associated bacteria.
The parameters examined also include 23 relevant antibiotic resistance genes from six classes of antibiotics. The dysbiosis index examines the balance between bacteria for health and disease. In addition, an algorithm checks the risk of progression of periodontitis and can thus assess the expected progression of the disease.
The balance between health- and disease-related bacteria indicates symbiotic or dysbiotic conditions. Only on the basis of this assessment via the dysbiosis index of the oral microbiome a real assessment and the change before clinical symptoms is possible.
The detection of bacteria in the gingival pocket according to the clinical situation is expectable. Only the identification of deviating microbial loads makes specific therapy possible and identifies high-risk patients who really benefit from adjuvant.
Dysbiosis in the microbiome
Antibiotic resistance
Optimized antibiotic indication
Health-associated / Disease-associated / Core species / Other species
Analysis of over 550 bacterial species
Main contributing bacteria with a proportion > 0.1%
Detection of pathogenic & highly pathogenic marker bacteria + Aa serotypes
Antibiotic resistance genes from six antibiotic classes relevant to dental care as indicators of treatment failure.
Check-up
Regular dental check-up without any need of treatment conclusion
Prophylaxis
Prophylaxis program with monitoring and regular screening
Therapy
Periodontal therapy with and without adjuvant (according to risk of progression).
The result recommendations are the essential component that really matters. With PadoBiom® it has been redesigned. Outcome recommendations take the form of classification into one of three practice-based categories, with procedures from the familiar dental treatment spectrum.
This makes it possible for the first time to decide at an early stage which patients belong from the check-up to prophylaxis or even from prophylaxis to therapy. This improves the success of the therapy and even prevents the need for therapy if the diagnosis is made at an early stage.
Use PadoBiom® to detect developing periodontitis at an early stage and, in cases of existing disease, to identify high-risk patients and antibiotic resistance.