Aggregatibacter actinomycetemcomitans diagnostics – for your personalized periodontal therapy.

With the PadoSero, you can determine the serotypes of Aggregatibacter actinomycetemcomitans, including the highly virulent JP2 clone and avoid overtreatment with antibiotics associated with this bacterium. Serotypes are variants within the species with different virulence. A distinction is made between serotypes a, b (JP2 clone if applicable), c, d, e, and f. Serotype a occurs with a high prevalence (25%) but has the lowest virulence and thus does not warrant antibiotic administration.

Now also available separately

To support a purely clinically indicated antibiosis, PadoSero can avoid the use of amoxicillin. You decide whether antibiotics are necessary on a purely clinical basis, PadoSero helps to avoid exposure to duplicate preparations (e.g. the Winkelhoff cocktail).

Modification of the therapy recommendation by using PadoSero

Detection of Aa

Antibiotics indicated


Detection of Aa serotype a

Antibiotics not indicated

(no amoxicillin)

How to order PadoSero?


PadoSero is included with PadoBiom® and PadoTest®, but can also be ordered separately by selecting it on the PadoTest® order form.

For more information on the PadoSero, please refer to our technical journal.


  • Our Aa diagnostics with the PadoSero are available as an optional addition to the regular PadoTest® and thus as a decision support for personalized therapy.
  • The option to PadoSero can be selected for each order, but will only be activated and billed if Aggregatibacter actinomycetemcomitans is detected.
  • Just mark the checkbox on the order form or make a handwritten note.

Type 4A Serotype a


If the PadoSero analyzes Aa of serotype a in type 4A, adjuvant administration of amoxicillin can be omitted.


The therapy recommendation changes from amoxicillin 500 mg 3 times daily for 7 days each to subgingival instrumentation without antibiotic indication.

Type 5B Serotype a


If the PadoSero analyzes Aa of serotype a in type 5B, adjuvant administration of amoxicillin can be omitted.


Therapy recommendation changes from metronidazole 3x daily each for 7 days (400 - 500 mg) + amoxicillin (500 mg) to metronidazole 3 x 400 - 500 mg, daily for 7 days.